Jumat, 25 November 2011

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Avastin For Lung Cancer Patients

Posted: 25 Nov 2011 08:30 AM PST


Avastin is one of the newer set of drugs, called anti-angiogenesis drugs. Drugs work, strangling the blood supply to the tumor. This prevents the tumor from creating new blood vessels and prevents their development. It is already approved for use in the treatment of colon cancer and lung cancer.
In the U.S., lung cancer is primarily a cause of cancer death, claiming more than 163,000 lives each year. Because the disease often does not exist, before it has spread, a large number of patients die within a year or two of diagnosis. Only 15% of patients alive five years after diagnosis were.


Avastin has proven survival benefits in many tumor types. In Europe, Avastin is approved to treat advanced stages of four common types of cancer: cancer of the colon, lung, breast, kidney and cancer. These cancers combined lead to nearly 3 million deaths annually. In the U.S., Avastin was the first anti-angiogenesis therapy approved by the FDA.


More than 500,000 patients treated with Avastin to the present. An extensive clinical program with more than 450 clinical trials examining the use of Avastin in many types of cancer (including colon, lung, stomach, prostate, breast, brain, ovarian cancer, and others).


It is currently being tested in many clinical trials, including the use of other targeted therapies in early-stage non-small cell lung cancer, the use of other types of chemotherapy after surgical removal of lung tumors, as a maintenance treatment.
The main side effect was severe bleeding in the lungs. It has been observed in other studies of Avastin in patients with lung cancer, especially in people with squamous cell lung cancer

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